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What Is Diabetic Nerve Pain of the Feet?

Diabetic nerve pain of the feet, also known as diabetic peripheral neuropathy of the feet, occurs if nerves are damaged as a result of diabetes. Damaged nerves cannot correctly transmit signals from the skin to the brain, causing the signals to become exaggerated and create the debilitating pain in your feet.

  • Although diabetic nerve pain can affect any nerve, it's most often felt in extremities, such as the feet
  • Patients have described diabetic nerve pain of the feet as "shooting electric shocks," "walking on broken glass," or “burning sensations"

You Are Not Alone

37 million

people live with diabetes*

10 million

people live with diabetic neuropathy

2.5 million

people live with diabetic nerve pain despite multiple treatments

*Source: Centers for Disease Control and Prevention. A snapshot: diabetes in America. Accessed March 30, 2022.
Source: University of Chicago Center for Peripheral Neuropathy. Types of peripheral neuropathy. Accessed March 30, 2022.

Discovering the QUTENZA Difference

The journey of finding relief from diabetic nerve pain of the feet can be a frustrating one – from the shooting pain and burning in your feet to multiple treatment methods that didn't improve your symptoms or had unwanted side effects.

Take the first step toward pain relief by talking to your doctor or healthcare professional about QUTENZA, the first and only treatment to deliver prescription-strength capsaicin directly to the skin.


QUTENZA® (capsaicin) 8% topical system is indicated in adults for the treatment of neuropathic pain associated with postherpetic neuralgia (PHN) and for neuropathic pain associated with diabetic peripheral neuropathy (DPN) of the feet.


Treatment with QUTENZA must be performed only by a healthcare provider. You should never apply or remove QUTENZA yourself.



Warnings and Precautions

  • Do not touch QUTENZA or items exposed to capsaicin. Touching QUTENZA and then accidentally touching other areas of your body can cause severe irritation of eyes, mucous membranes, respiratory tract, and skin.
  • QUTENZA is not for use near eyes or mucous membranes. Do not sniff or inhale near QUTENZA as this may cause you to cough or sneeze.
  • If any of these side effects become severe, tell your healthcare provider immediately.
  • Even though a numbing medicine is used on the skin before applying QUTENZA, some patients may still experience substantial pain during the treatment. Tell your healthcare provider if you are experiencing pain; a cool compress or medicine for the pain can be provided to help lessen your discomfort.
  • QUTENZA can cause serious side effects, including pain and increases in blood pressure during or right after treatment.
  • Your healthcare provider should check your blood pressure during treatment with QUTENZA.
  • If you have high blood pressure that is not well controlled by medicine, or have had recent heart problems, stroke, or other vascular problems, you may be at increased risk and should discuss with your doctor whether QUTENZA is right for you.
  • Tell your doctor if you have reduced sensation in the feet. You may notice that you have less feeling for hot or sharp pain where QUTENZA was applied, but this is usually minor and temporary.

Side Effects

In all clinical trials, the most common drug-related side effects of QUTENZA were redness, pain, or itching where QUTENZA was applied. You should tell your doctor if any side effects bother you or do not go away.

Adverse Event Reporting

Physicians, other healthcare providers, and patients are encouraged to voluntarily report adverse events involving drugs or medical devices. To make a report you can:

  • In the US, visit or call 1-800-FDA-1088; or
  • For QUTENZA, you may also call 1-877-900-6479 and select option 1, or press zero on your keypad to talk to an operator to direct your call.

For more information, ask your healthcare provider or pharmacist.

Please see full Prescribing Information.

  • Carton with one topical system + Cleansing Gel: NDC #72512-928-01
  • Carton with two topical systems + Cleansing Gel: NDC #72512-929-01
  • Carton with four topical systems + Cleansing Gel: NDC #72512-930-01